Database analysis of depression and anxiety in a community sample—response to a micronutrient intervention

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dc.contributor.authorKimball SM
dc.contributor.authorMirhosseini N
dc.contributor.authorRucklidge J
dc.date.accessioned2019-10-01T22:27:43Z
dc.date.available2019-10-01T22:27:43Z
dc.date.issued2018en
dc.date.updated2018-10-31T19:28:54Z
dc.description.abstractBackground: Depression and anxiety are common mental health concerns worldwide. Broad-spectrum multi-vitamin/mineral approaches have been found to alleviate a number of psychiatric symptoms. We investigated the effects of a nutrient intervention program, which includes optimizing vitamin D levels, on depression and anxiety outcomes from community-based program. Methods: We evaluated self-reported health measures of depression and anxiety collected as part of a community-based program focused on optimizing overall health through nutritional supplementation, education and lifestyle advice. Results: Data were collected from 16,020 participants, with measures including European Quality of Life Five Dimensions (EQ-5D) and Targeted Symptoms List (TSL) providing self-reported depression and anxiety. More than 56% of participants were identified as having elevated levels of depression and anxiety at baseline as reported on the EQ-5D. After one year in the program, 49.2% (n = 7878) of participants who reported any level of depression or anxiety at baseline reported improvement at follow-up. Of those who reported severe/extreme depression at baseline (n = 829), 97.2% reported improvement after one year. Regression analyses revealed a significant association of improvement in depression and anxiety with higher vitamin D status (>100 nmol/L) and more strenuous physical activity. Conclusion: Overall, people from the general population who suffer from mood and anxiety problems may benefit from improved nutritional status achieved with nutritional supplements.en
dc.identifier.doihttps://doi.org/10.3390/nu10020152
dc.identifier.issn2072-6643
dc.identifier.urihttp://hdl.handle.net/10092/17357
dc.languageEnglish
dc.language.isoen
dc.rights© 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).en
dc.subjectHumansen
dc.subjectMicronutrientsen
dc.subjectCombined Modality Therapyen
dc.subjectExerciseen
dc.subjectPrevalenceen
dc.subjectCase-Control Studiesen
dc.subjectFollow-Up Studiesen
dc.subjectProgram Evaluationen
dc.subjectHealth Knowledge, Attitudes, Practiceen
dc.subjectDepressionen
dc.subjectAnxietyen
dc.subjectAnxiety Disordersen
dc.subjectDepressive Disorder, Majoren
dc.subjectPsychiatric Status Rating Scalesen
dc.subjectQuality of Lifeen
dc.subjectDietary Supplementsen
dc.subjectAdulten
dc.subjectAgeden
dc.subjectMiddle Ageden
dc.subjectHealth Promotionen
dc.subjectCanadaen
dc.subjectFemaleen
dc.subjectMaleen
dc.subjectYoung Adulten
dc.subjectElectronic Health Recordsen
dc.subjectHealthy Lifestyleen
dc.subject.anzsrcField of Research::17 - Psychology and Cognitive Sciences::1701 - Psychology::170106 - Health, Clinical and Counselling Psychologyen
dc.subject.anzsrcField of Research::11 - Medical and Health Sciences::1111 - Nutrition and Dieteticsen
dc.titleDatabase analysis of depression and anxiety in a community sample—response to a micronutrient interventionen
dc.typeJournal Articleen
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