Comparison of adaptive and sliding-scale glycaemic control in critical care and the impact of nutritional inputs

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dc.contributor.authorWong, X-W.
dc.contributor.authorChase, Geoff
dc.contributor.authorShaw, Geoff
dc.contributor.authorHann, C.E.
dc.contributor.authorLin, J.
dc.contributor.authorLotz, T.
dc.date.accessioned2007-07-06T00:07:55Z
dc.date.available2007-07-06T00:07:55Z
dc.date.issued2005en
dc.description.abstractStress-induced hyperglycaemia is prevalent in critical care. Tight glucose control can reduce mortality up to 43%. An adaptive control algorithm utilising insulin and nutritional feed inputs for targeted glycaemic control in critically ill patients is presented. Validation is performed using retrospective patient data (n=19) in simulated glucoregulatory trials. Conventional sliding-scale and insulin-only methods are compared. Results show a reduction in mean glucose levels, and variability. A 312% increase in time spent in the 4- 6mmol/L normal glucose band compared to sliding scale and a 240% increase compared to the insulin only protocol is reported. Results are obtained using 60% more insulin and 20% more nutrition across a wide cross-section of ICU patients and patient condition, indicating that the timing of control input administration is more crucial than their absolute amounts. The results show potential in reducing ICU mortality and the risk of severe complications.en
dc.identifier.citationWong, X.W., Chase, J.G., Shaw, G.M., Hann, C.E., Lin, J., Lotz, T. (2005) Comparison of adaptive and sliding-scale glycaemic control in critical care and the impact of nutritional inputs. Singapore: 12th International Conference On Biomedical Engineering, 7-10 Dec 2005. 2A5-06, 4 pp.en
dc.identifier.urihttp://hdl.handle.net/10092/157
dc.language.isoen
dc.publisherUniversity of Canterbury. Mechanical Engineering.en
dc.relation.urihttp://www.icbme.org/en
dc.rights.urihttps://hdl.handle.net/10092/17651en
dc.subject.marsdenFields of Research::230000 Mathematical Sciences::230100 Mathematics::230119 Systems theory and controlen
dc.subject.marsdenFields of Research::290000 Engineering and Technology::290500 Mechanical and Industrial Engineering::290501 Mechanical engineeringen
dc.subject.marsdenFields of Research::320000 Medical and Health Sciences::321000 Clinical Sciences::321008 Haematologyen
dc.subject.marsdenFields of Research::320000 Medical and Health Sciences::320600 Medical Physiology::320699 Medical physiology not elsewhere classifieden
dc.titleComparison of adaptive and sliding-scale glycaemic control in critical care and the impact of nutritional inputsen
dc.typeConference Contributions - Published
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