Noise Considerations for Tomographic Reconstruction of Single-Projection Digital Holographic Interferometry-Based Radiation Dosimetry

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dc.contributor.authorMoggré A
dc.contributor.authorTelford, Thomas
dc.contributor.authorRoberts, Jackson
dc.contributor.authorMeyer, Juergen
dc.contributor.authorMarsh, Steven
dc.date.accessioned2023-03-16T21:37:34Z
dc.date.available2023-03-16T21:37:34Z
dc.date.issued2023en
dc.date.updated2023-02-13T21:41:36Z
dc.description.abstractOptical Calorimetry (OC) is a 2D Digital Holographic Interferometry (DHI)-based measurement technique with potential applications for the 3D dosimetry of ultra-high dose rate (FLASH) radiation therapy beams through tomographic reconstruction. This application requires accurate measurements of DHI signals in environments with low signal-to-noise ratios (SNRs) in order to accurately measure absorbed energy to a medium per unit mass (Dose). However, tomographic reconstruction accuracy is sensitive to noise in the measurements. In this study, a virtual model of an OC dosimeter was used to characterize and model major sources of noise within a DHI setup, allowing for the modelled noise sources to be selectively reduced. The tomographic reconstruction of the 3D dose distribution was achieved using the inverse Abel transform. Reducing the noise contribution from atmospheric turbulence and mechanical vibration by one half improved the central axis reconstruction error from 6.5% to 1.3% and 1.1%, respectively, and the mean dose difference from 2.9% to 0.4% and 0.3%, respectively. This indicates the potential of the tomographic DHI-based 3D OC dosimeter to reconstruct accurate 3D dose distributions from a single projection if the specified sources of noise can be reduced to acceptable levels. The used methodology is applicable to any application of tomographic DHI where reconstruction quality is highly sensitive to noise.en
dc.identifier.citationTelford T, Roberts J, Moggré A, Meyer J, Marsh S (2023). Noise Considerations for Tomographic Reconstruction of Single-Projection Digital Holographic Interferometry-Based Radiation Dosimetry. Photonics. 10(2). 188-188.en
dc.identifier.doihttp://doi.org/10.3390/photonics10020188
dc.identifier.issn2304-6732
dc.identifier.urihttps://hdl.handle.net/10092/105238
dc.languageen
dc.language.isoenen
dc.publisherMDPI AGen
dc.rightsAll rights reserved unless otherwise stateden
dc.rights.urihttp://hdl.handle.net/10092/17651en
dc.subjectDigital Holographic Interferometryen
dc.subjecttomographyen
dc.subjectradiation dosimetryen
dc.subjectinverse Abel transformen
dc.subjectFREDen
dc.subjectOptical Calorimetryen
dc.subject.anzsrcFields of Research::32 - Biomedical and clinical sciences::3202 - Clinical sciences::320222 - Radiology and organ imagingen
dc.subject.anzsrcFields of Research::32 - Biomedical and clinical sciences::3211 - Oncology and carcinogenesis::321110 - Radiation therapyen
dc.subject.anzsrcFields of Research::51 - Physical sciences::5105 - Medical and biological physics::510502 - Medical physicsen
dc.titleNoise Considerations for Tomographic Reconstruction of Single-Projection Digital Holographic Interferometry-Based Radiation Dosimetryen
dc.typeJournal Articleen
uc.collegeFaculty of Science
uc.departmentSchool of Physical & Chemical Sciences
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