Aminoalkylation of nitriles by iminium ions generated in situ (2006)
AuthorsKatritzky, A.R., Abdel-Fattah, A.A.A., Steel, P.J.show all
Aminoalkylation of a series of primary and secondary nitriles with N-(α-aminoalkyl)benzotriazoles 1 (derived from a variety of secondary amines and aldehydes) proceeds smoothly providing the corresponding β-aminoalkyl nitriles 5a–j in 66–97% yields.
CitationKatritzky, A.R., Abdel-Fattah, A.A.A, Steel, P.J. (2006) Aminoalkylation of nitriles by iminium ions generated in situ. Tetrahedron Letters, 47(9), pp. 1465-1467.
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