Long-Term cost-effectiveness analysis of rugby fans in training-New Zealand: A body weight reduction programme for males

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dc.contributor.authorLee , Peter
dc.contributor.authorHargreaves , Elaine
dc.contributor.authorJiang , Yannan
dc.contributor.authorCalder , Amanda
dc.contributor.authorMarsh , Samantha
dc.contributor.authorGray , Cindy
dc.contributor.authorHunt , Kate
dc.contributor.authorEyles , Helen
dc.contributor.authorDraper, Nick
dc.contributor.authorHeke , Ihirangi
dc.contributor.authorKara , Stephen
dc.contributor.authorMaddison , Ralph
dc.contributor.authorGao , Lan
dc.date.accessioned2024-11-26T00:05:27Z
dc.date.available2024-11-26T00:05:27Z
dc.date.issued2024
dc.description.abstractObjectives We sought to extrapolate the long-Term costs and clinical impacts attributed to the rugby fans in training-New Zealand (RUFIT-NZ) trial in Aotearoa, New Zealand. Design A modelled cost-effectiveness analysis using efficacy data from RUFIT-NZ was conducted from the Aotearoa New Zealand healthcare perspective. Setting A Markov cohort model was constructed with a lifetime time horizon. The model simulated events of myocardial infarction (MI), stroke and type 2 diabetes mellitus (T2DM) occurring among a hypothetical cohort of 10 000 individuals receiving either the RUFIT-NZ intervention or no intervention. Efficacy data were based on the RUFIT-NZ trial, and the latest Global Burden of Disease study was used to extrapolate the impact of body weight reduction on clinical outcomes of T2DM, MI or stroke. Cost and utility data were drawn from the RUFIT-NZ trial and published sources. Primary outcome measures The incremental cost-effectiveness ratio (ICER). Results Over a lifetime time horizon, participants in the RUFIT-NZ intervention gained 0.02 (discounted) quality-Adjusted life years (QALYs) at an additional cost of NZ$863, relative to no intervention. The estimated ICER was NZ$49 515 per QALY gained (discounted), which is above the arbitrary willingness-To-pay threshold of NZ$45 000 per QALY. Sensitivity analyses supported the robustness of these findings. Conclusions RUFIT-NZ was associated with a reduction in cardiovascular and endocrine events for overweight and obese males. However, based on conservative assumptions, RUFIT-NZ was unlikely to be cost-effective from a healthcare system perspective. Trial registration number ACTRN12619000069156.
dc.identifier.citationLee P, Hargreaves E, Jiang Y, Calder A, Marsh S, Gray C, Hunt K, Eyles H, Draper N, Heke I, Kara S, Maddison R, Gao L (2024). Long-Term cost-effectiveness analysis of rugby fans in training-New Zealand: A body weight reduction programme for males. BMJ Open. 14(7). e073740-.
dc.identifier.doihttp://doi.org/10.1136/bmjopen-2023-073740
dc.identifier.issn2044-6055
dc.identifier.urihttps://hdl.handle.net/10092/107618
dc.languageeng
dc.publisherBMJ
dc.rightsAll rights reserved unless otherwise stated
dc.rights.urihttp://hdl.handle.net/10092/17651
dc.subjectHumans
dc.subjectMyocardial Infarction
dc.subjectDiabetes Mellitus, Type 2
dc.subjectWeight Loss
dc.subjectMarkov Chains
dc.subjectQuality-Adjusted Life Years
dc.subjectAdult
dc.subjectAged
dc.subjectMiddle Aged
dc.subjectCost-Benefit Analysis
dc.subjectNew Zealand
dc.subjectMale
dc.subjectStroke
dc.subjectWeight Reduction Programs
dc.subjectRugby
dc.subjectCost-Effectiveness Analysis
dc.subject.anzsrc42 - Health sciences::4206 - Public health::420605 - Preventative health care
dc.subject.anzsrc32 - Biomedical and clinical sciences::3210 - Nutrition and dietetics::321002 - Food properties (incl. characteristics and health benefits)
dc.titleLong-Term cost-effectiveness analysis of rugby fans in training-New Zealand: A body weight reduction programme for males
dc.typeJournal Article
uc.collegeFaculty of Health
uc.departmentSchool of Health Sciences
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