Model-based therapeutics for the Cardiovascular System - a Clinical Focus

Simple item page
dc.contributor.authorHann, C.E.
dc.contributor.authorChase, Geoff
dc.contributor.authorDesaive, T.
dc.contributor.authorLambermont, B.
dc.contributor.authorGhuysen, A.
dc.contributor.authorKolh, P.
dc.contributor.authorShaw, Geoff
dc.date.accessioned2010-04-20T21:45:36Z
dc.date.available2010-04-20T21:45:36Z
dc.date.issued2009en
dc.description6-pages (invited)en
dc.description.abstractThis paper focuses on clinical results of a model-based cardiac diagnosis and therapy methodology. The method allows for accurate patient specific identification and prediction of a broad range of hemodynamics typical in the critically ill. Extensive porcine experiments have been performed involving drug induced pulmonary embolism and septic shock including hemofiltration therapy. The model-based methods consistently capture all measured cardiac variables, within 5-10% error throughout the experiments. Importantly, all the physiologically expected responses to pulmonary embolism and septic shock are captured and compare well to more directly measured but highly invasive procedures. The cardiovascular system model only requires clinical data that is readily available in the Intensive Care Unit. Therefore, the results demonstrate the potential for longer term developing a cardiac diagnosis and therapeutic guidance system for use in critical care at the bedside.en
dc.identifier.citationHann, C.E., Chase, J.G., Desaive, T., Lambermont, B., Ghuysen, A., Kolh, P., Shaw, G.M. (2009) Model-based therapeutics for the Cardiovascular System - a Clinical Focus. Aalborg, Denmark: 7th IFAC Symposium on Modeling and Control in Biomedical Systems (MCBMS09), 12-14 Aug 2009.en
dc.identifier.urihttp://hdl.handle.net/10092/3783
dc.language.isoen
dc.publisherUniversity of Canterbury. Mechanical Engineeringen
dc.rights.urihttps://hdl.handle.net/10092/17651en
dc.subject.marsdenFields of Research::320000 Medical and Health Sciences::321000 Clinical Sciences::321003 Cardiology (incl. cardiovascular disease)en
dc.subject.marsdenFields of Research::320000 Medical and Health Sciences::321000 Clinical Sciences::321009 Intensive careen
dc.subject.marsdenFields of Research::290000 Engineering and Technology::291500 Biomedical Engineering::291504 Biomechanical engineeringen
dc.subject.marsdenFields of Research::290000 Engineering and Technology::290900 Electrical and Electronic Engineering::290901 Electrical engineeringen
dc.titleModel-based therapeutics for the Cardiovascular System - a Clinical Focusen
dc.typeConference Contributions - Other
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
12622136_Chase.pdf
Size:
905.68 KB
Format:
Adobe Portable Document Format
Download
Collections
Engineering: Conference Contributions