Glargine as a Basal Insulin Supplement in Recovering Critically Ill Patients - An In Silico Study

Type of content
Conference Contributions - Published
Publisher's DOI/URI
Thesis discipline
Degree name
Publisher
University of Canterbury. Mechanical Engineering
Journal Title
Journal ISSN
Volume Title
Language
Date
2010
Authors
Razak, N.N.
Lin, J.
Chase, Geoff
Shaw, Geoff
Pretty, C.G.
Le Compte, A.J.
Suhaimi, F.M.
Jamaludin, U.
Abstract

Tight glycaemic control is now benefiting medical and surgical intensive care patients by reducing complications associated with hyperglycaemia. Once patients leave this intensive care environment, less acute wards do not continue to provide the same level of glycaemic control. Main reason is that these less acute wards do not have the high levels of nursing resources to provide the same level of glycaemic control. Therefore developments in protocols that are less labour intensive are necessary. This study examines the use of insulin glargine for basal supplement in recovering critically ill patients. These patients represent a group who may benefit from such basal support therapy. In silico study results showed the potential in reducing nursing effort with the use of glargine. However, a protocol using only glargine for glucose control did not show to be effective in the simulated patients. This may be an indication that a protocol using only glargine is more suitable after discharge from critical care.

Description
Citation
Razak, N.N., Lin, J., Chase, J.G., Shaw, G.M., Pretty, C.G., Le Compte, A.J., Suhaimi, F.M., Jamaludin, U. (2010) Glargine as a Basal Insulin Supplement in Recovering Critically Ill Patients - An In Silico Study. Coventry, UK: UKACC International Conference on CONTROL 2010, 7-10 Sep 2010.
Keywords
hyperglycaemia, insulin glargine, tight glycaemic control, SPRINT, critical care
Ngā upoko tukutuku/Māori subject headings
ANZSRC fields of research
Fields of Research::32 - Biomedical and clinical sciences::3205 - Medical biochemistry and metabolomics::320502 - Medical biochemistry - carbohydrates
Fields of Research::32 - Biomedical and clinical sciences::3202 - Clinical sciences::320212 - Intensive care
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