Micro- and Nanopatterning of Freestanding Protein Films

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dc.contributor.authorHashemi, A.
dc.contributor.authorTay, D.
dc.contributor.authorMutreja, I.
dc.contributor.authorAli, M.A.
dc.contributor.authorAlkaisi, M.M.
dc.contributor.authorNock, V.
dc.date.accessioned2017-01-04T01:08:07Z
dc.date.available2017-01-04T01:08:07Z
dc.date.issued2015en
dc.description.abstractBiodegradable casein films have significant potential for use as non-supported stand-alone sheeting in orthopaedic implants and tissue engineering substrates. Multi-scale surface patterns can be used to modulate and guide cell interaction by means of an engineered construct. The majority of work on cell-pattern interaction has so far focused on non-degradable materials. In this paper we demonstrate for the first time the fabrication of micro- and nano-scale geometric patterns on the surface of a crosslinked biodegradable casein film. To achieve this we introduce a two-step fabrication procedure based on polydimethylsiloxane (PDMS) soft-lithography. We will show the reproduction of micro- and nano-scale patterns in liquid-cast casein films. We also demonstrate film formation and cross-linking using glutaraldehyde and discuss the use of these films as cell-culture substrates.en
dc.identifier.citationHashemi, A., Tay, D., Mutreja, I., Ali, M.A., Alkaisi, M.M., Nock, V. (2015) Micro- and Nanopatterning of Freestanding Protein Films. Nelson, New Zealand: 7th International Conference on Nanotechnology and Advanced Materials (AMN-7), 8-12 Feb 2015.en
dc.identifier.urihttp://hdl.handle.net/10092/12960
dc.language.isoen
dc.publisherUniversity of Canterbury. Electrical and Computer Engineeringen
dc.publisherUniversity of Canterbury. Biomolecular Interaction Centreen
dc.rights.urihttps://hdl.handle.net/10092/17651
dc.subject.anzsrcField of Research::10 - Technology::1004 - Medical Biotechnology::100404 - Regenerative Medicine (incl. Stem Cells and Tissue Engineering)en
dc.subject.anzsrcFields of Research::40 - Engineering::4018 - Nanotechnology::401805 - Nanofabrication, growth and self assemblyen
dc.titleMicro- and Nanopatterning of Freestanding Protein Filmsen
dc.typeConference Contributions - Other
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