The acid hydrolysis of oxamic acid and oxamide

Type of content
Theses / Dissertations
Publisher's DOI/URI
Thesis discipline
Chemistry
Degree name
Master of Science
Publisher
University of Canterbury. Chemistry
Journal Title
Journal ISSN
Volume Title
Language
Date
1951
Authors
Thomson, A. L.
Abstract

Samples of oxamic acid and oxamide, the mono- and di-amide of oxalic acid respectively, have been prepared and purified. The kinetics of hydrolysis of these amides in hydrochloric acid solutions, 0.25 – 0.75 molar, have been studied and the results explained theoretically. A qualitative and quantitative investigation of the hydrolysis products have been carried out and the results used to disprove a theory of the reaction course suggested by McKenzie to explain apparent anomalies in the kinetics. A possible mechanism for amide hydrolysis has been put forward and discussed along with supporting evidence. The relative effects of a carboxyl and an amide group on a neighbouring group have been discussed and it has been concluded that the amide group is the less electron attracting of the two.

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Citation
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Ngā upoko tukutuku/Māori subject headings
ANZSRC fields of research
Rights
Copyright A. L. Thomson