Assessment of ventricular contractility and ventricular-arterial coupling with a model-based sensor (2013)
Type of ContentJournal Article
PublisherUniversity of Canterbury. Mechanical Engineering
Estimation of ventricular contractility and ventricular arterial coupling is clinically important in diagnosing cardiac dysfunction in the critically ill. However, experimental assessment of indexes of ventricular contractility, such as the end-systolic pressure-volume relationship requires a highly invasive maneuver. This research describes the use of a previously validated cardiovascular system (CVS) model and identification process to evaluate the right ventricular arterial coupling in septic shock. The results show good agreement with the gold-standard experimental assessment (conductance catheter method), and offer the potential to develop a model-based sensor to monitor the coupling in clinical real-time.
CitationDesaive, T., Lambermont, B., Janssen, N., Ghuysen, A., Kolh, P., Morimont, P., Dauby, P.C., Starfinger, C., Shaw, G.M., Chase, J.G. (2013) Assessment of ventricular contractility and ventricular-arterial coupling with a model-based sensor. Computer Methods and Programs in Biomedicine, 109(2), pp. 182-189.
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Keywordscardiovascular; model; intensive care; sensor; ventricular function; ICU
ANZSRC Fields of Research32 - Biomedical and clinical sciences::3201 - Cardiovascular medicine and haematology::320102 - Haematology
32 - Biomedical and clinical sciences::3201 - Cardiovascular medicine and haematology::320101 - Cardiology (incl. cardiovascular diseases)
32 - Biomedical and clinical sciences::3202 - Clinical sciences::320212 - Intensive care
40 - Engineering::4017 - Mechanical engineering::401706 - Numerical modelling and mechanical characterisation
Showing items related by title, author, creator and subject.
Arterial dP/dt_max accurately reflects left ventricular contractility during shock when adequate vascular filling is achieved Morimont, P.; Lambermont, B.; Desaive, T.; Chase, Geoff; D'Orio, V.; Janssen, N. (University of Canterbury. Mechanical Engineering, 2012)Background: Peak first derivative of femoral artery pressure (arterial dP/dtmax) derived from fluid-filled catheter remains questionable to assess left ventricular (LV) contractility during shock. The aim of this study ...
Subject-specific cardiovascular system model-based identification and diagnosis of septic shock with a minimally invasive data set: Animal experiments and proof of concept Chase, Geoff; Lambermont, B.; Starfinger, C.; Hann, C.E.; Shaw, Geoff; Ghuysen, A.; Kolh, P.; Dauby, P.C.; Desaive, T. (University of Canterbury. Electrical and Computer EngineeringUniversity of Canterbury. Mechanical Engineering, 2011)A cardiovascular system (CVS) model and parameter identification method have previously been validated for identifying different cardiac and circulatory dysfunctions in simulation and using porcine models of pulmonary ...
Revie, J.A.; Stevenson, D.; Chase, Geoff; Pretty, C.G.; Lambermont, B.C.; Ghuysen, A.; Kolh, P.; Shaw, Geoff; Desaive, T. (University of Canterbury. Mechanical Engineering, 2013)Introduction. The accuracy and clinical applicability of an improved model-based system for tracking hemodynamic changes is assessed in an animal study on septic shock. Methods. This study used cardiovascular measurements ...