Optimal tight glycaemic control supported by differential geometric methods

Type of content
Conference Contributions - Published
Thesis discipline
Degree name
Publisher
University of Canterbury. Mechanical Engineering
Journal Title
Journal ISSN
Volume Title
Language
Date
2011
Authors
Kovacs, L.
Szalay, P.
Benyo, B.
Chase, Geoff
Abstract

Optimal control of an Intensive Care Unit (ICU) metabolic model from nonlinear control point of view is presented in the current paper. The transformation of a clinically validated nonlinear model into a series of integrators via exact linearization and asymptotic output tracking is performed. Both methods need the value of the state variables; therefore Kalman-filter extended for nonlinear systems is applied. Finally, linear optimal LQ method is applied on the ICU model handled with differential geometric approach. Results are demonstrated on input data recorded in actual clinical environment.

Description
Citation
Kovacs, L, Szalay, P, Benyo, B and Chase, JG (2011) Optimal tight glycaemic control supported by differential geometric methods. Budapest, Hungary: 5th European Conference of IFMBE for Medical and Biological Engineering (MBEC), 14-18 Sept 2011. 4-pages.
Keywords
exact linearization, ICU model, asymptotic tracking, Kalman-filtering, LQ control
Ngā upoko tukutuku/Māori subject headings
ANZSRC fields of research
Field of Research::09 - Engineering::0903 - Biomedical Engineering
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