Insulin + nutrition control for tight critical care glycaemic regulation
Type of content
Conference Contributions - Published
UC permalink
Publisher's DOI/URI
Thesis discipline
Degree name
Publisher
University of Canterbury. Mathematics and Statistics.
University of Canterbury. Mechanical Engineering.
University of Canterbury. Mechanical Engineering.
Journal Title
Journal ISSN
Volume Title
Language
Date
2006
Authors
Chase, Geoff
Wong, J.
Lin, J.
LeCompte, A.
Lotz, T.
Lonergan, T.
Willacy, M.B.
Hann, C.E.
Shaw, Geoff
Abstract
A new insulin and nutrition control method for tight glycaemic control in critical care is presented from concept to clinical trials to clinical practice change. The primary results show that the method can provide very tight glycaemic control in critical care for a very critically ill cohort. More specifically, the final clinical practice change protocol provided 2100 hours of control with average blood glucose of 5.8 +/- 0.9 mmol/L for an initial 10 patient pilot study. It also used less insulin, while providing the same or greater nutritional input, as compared to retrospective hospital control for a relatively very critically ill cohort with high insulin resistance.
Description
Citation
Chase, J.G., Wong, J., Lin, J., LeCompte, A., Lotz, T., Lonergan, T., Willacy, M., Hann, C.E., Shaw, G.M. (2006) Insulin + nutrition control for tight critical care glycaemic regulation. Reims, France: 6th IFAC Symposium on Modelling and Control in Biomedical Systems (Including Biological Sciences) (MCBMS'06), 19-22 Sep 2006. 6 pp.
Keywords
Biomedical control, Control algorithms, Non-linear models, Physiological models, Physiology, Medical systems