A Polynomial Model of Patient-specific Breathing Effort During Controlled Mechanical Ventilation (2015)
Type of ContentConference Contributions - Other
PublisherUniversity of Canterbury. Mechanical Engineering
AuthorsRedmond, D.P., Docherty, P.D., Chiew, Y.S., Chase, J.G.show all
Patient breathing efforts occurring during controlled ventilation causes perturbations in pressure data, which cause erroneous parameter estimation in conventional models of respiratory mechanics. A polynomial model of patient effort can be used to capture breath-specific effort and underlying lung condition. An iterative multiple linear regression is used to identify the model in clinical volume controlled data. The polynomial model has lower fitting error and more stable estimates of respiratory elastance and resistance in the presence of patient effort than the conventional single compartment model. However, the polynomial model can converge to poor parameter estimation when patient efforts occur very early in the breath, or for long duration. The model of patient effort can provide clinical benefits by providing accurate respiratory mechanics estimation and monitoring of breath-to-breath patient effort, which can be used by clinicians to guide treatment.
CitationRedmond, D.P., Docherty, P.D., Chiew, Y.S., Chase, J.G. (2015) A Polynomial Model of Patient-specific Breathing Effort During Controlled Mechanical Ventilation. Milan, Italy: 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 25-29 Aug 2015.
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ANZSRC Fields of Research09 - Engineering::0903 - Biomedical Engineering::090302 - Biomechanical Engineering
11 - Medical and Health Sciences::1102 - Cardiovascular Medicine and Haematology::110203 - Respiratory Diseases