• Admin
    UC Research Repository
    View Item 
       
    • UC Home
    • Library
    • UC Research Repository
    • College of Science
    • Science: Theses and Dissertations
    • View Item
       
    • UC Home
    • Library
    • UC Research Repository
    • College of Science
    • Science: Theses and Dissertations
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of the RepositoryCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

    Statistics

    View Usage Statistics

    Investigation of C-type natriuretic peptide in the intact rat brain under formal and informal learning conditions

    Thumbnail
    View/Open
    Thesis_fulltext.pdf (994.5Kb)
    Rapley_Use_of_thesis_form.pdf (103.9Kb)
    Author
    Rapley, Susan Ann
    Date
    2012
    Permanent Link
    http://hdl.handle.net/10092/7882
    Thesis Discipline
    Psychology
    Degree Grantor
    University of Canterbury
    Degree Level
    Masters
    Degree Name
    Master of Science

    C-type Natriuretic Peptide (CNP), a relatively new member of the natriuretic peptide family, is found throughout the central nervous system. Circumstantial evidence associates CNP with learning and memory, as its expression is highest in brain regions known to be involved in memory and associated with hippocampal physiology. Here, the first study housed rats in an enriched environment, regarded as providing an 'informal' learning experience, for either 14 or 28 days of housing in enrichment in six regions of interest, which was attributed to changes in the degradation of CNP. The second study examined a group of rats trained on object -recognition task – the bow-tie maze. A difference was found in CNP production in the limbic medial prefrontal cortex over repeated exposures to novel objects relative to controls that received 'yoked learning' an exposure only to the test room. CNP concentrations also tended to be lower in rats with better levels of discrimination between familiar objects. Together, these studies provide some initial evidence that CNP influences learning –induced plasticity in the intact brain.

    Subjects
    C-type Natriuretic Peptide
     
    Environmental Enrichment
     
    Recognition memory
     
    Neuroplasticity
    Collections
    • Science: Theses and Dissertations [3603]
    Rights
    https://canterbury.libguides.com/rights/theses

    UC Research Repository
    University Library
    University of Canterbury
    Private Bag 4800
    Christchurch 8140

    Phone
    364 2987 ext 8718

    Email
    ucresearchrepository@canterbury.ac.nz

    Follow us
    FacebookTwitterYoutube

    © University of Canterbury Library
    Send Feedback | Contact Us