Now showing items 1-4 of 4
Ligand binding to a G protein–coupled receptor captured in a mass spectrometer
Copyright © 2017 The Authors, some rights reserved. G protein (heterotrimeric guanine nucleotide–binding protein)–coupled receptors belong to the largest family of membrane-embedded cell surface proteins and are involved ...
Lipid binding attenuates channel closure of the outer membrane protein OmpF
© 2018 National Academy of Sciences. All Rights Reserved. Strong interactions between lipids and proteins occur primarily through association of charged headgroups and amino acid side chains, rendering the protonation ...
Supplementation of blackcurrant anthocyanins increased cyclic glycine-proline in the cerebrospinal fluid of Parkinson patients: Potential treatment to improve insulin-like growth factor-1 function
© 2018 by the authors. Licensee MDPI, Basel, Switzerland. Background: Insulin-like growth factor-1 (IGF-1) function is impaired in Parkinson disease. Cyclic glycine-proline (cGP), a metabolite of IGF-1, is neuroprotective ...
L,L-diaminopimelate aminotransferase (DapL): a putative target for the development of narrow-spectrum antibacterial compounds.
(University of Canterbury. Biological SciencesUniversity of Canterbury. Biomolecular Interaction Centre, 2014)
Despite the urgent need for sustained development of novel antibacterial compounds to combat the drastic rise in antibiotic resistant and emerging bacterial infections, only a few clinically relevant antibacterial drugs ...