Now showing items 1-3 of 3
Mechanisms of 7,8-dihydroneopterin protection of macrophages from cytotoxicity
(University of Canterbury. Biological Sciences, 2013)
Gamma-interferon stimulates human macrophages to produce of 7,8-dihydroneopterin (7,8-NP). 7,8-NP and its oxidation product neopterin are excellent inflammatory markers for a variety of chronic conditions, including ...
A model of complex plaque formation: 7,8-Dihydroneopterin protects human monocyte-derived macrophages from oxidised low density lipoprotein-induced death
(University of Canterbury. School of Biological Sciences, 2008)
Plasma neopterin is an excellent marker of inflammation and is found in elevated levels in plasma of patients with cardiovascular disease. Neopterin originates as the oxidation product of 7,8-dihydroneopterin (7,8-NP), ...
Formation, Transport and Detection of 7,8-Dihydroneopterin
(University of Canterbury. School of Biological Sciences, 2013)
Atherosclerosis is a chronic inflammatory disease leading to plaque buildup in the major arteries. The plaques consist of cholesterol, calcium, inflammatory cells, extracellular matrix and fibrous material. Under ...