mAGiC DRAGONS: A Protocol for Accurate Glycaemic Control in General Wards

Simple item page
dc.contributor.authorThomas, F.L.
dc.contributor.authorWatson, A.
dc.contributor.authorTomlinson, H.
dc.contributor.authorBorowczyk, H.
dc.contributor.authorPretty, C.G.
dc.contributor.authorFisk, L.
dc.contributor.authorDickson, J.L.
dc.contributor.authorChiew, Y.S.
dc.contributor.authorShaw, Geoff
dc.contributor.authorChase, Geoff
dc.date.accessioned2014-09-16T23:59:25Z
dc.date.available2014-09-16T23:59:25Z
dc.date.issued2014en
dc.description.abstractAccurate glycaemic control (AGC) has been shown to be beneficial to the outcomes of critically ill patients. These benefits may also extend to patients in less acute wards, particularly those with existing diabetes. However, the clinical demands of an intensive care glycaemic control protocol are not appropriate for the general wards where the nurse-to-patient ratio is much lower and patients do not typically have an intravenous line available for insulin delivery. Thus, there is a need for a safe, effective glycemic control protocol tailored to the needs of general wards to enable appropriate care for diabetic patients and further testing of the benefits of glycaemic control for this cohort. This paper presents the development and testing of such a protocol for glycaemic control in the general wards. The DRAGONS protocol (Dynamic Regulation for Accurate Glycaemic-control Optimising iNsulin Subcutaneously) was designed to use subcutaneous insulin and only require blood glucose (BG) measurements every four hours, while maintaining BG concentrations within the range 4.4-8.0 mmol/L. Virtual trial simulation indicated an expected time in the target band of 73.0%, with < 2% risk of BG < 4.0 mmol/L. In the first patient recruited to the pilot trial, the DRAGONS protocol achieved 46% time in band and no severe hypoglycaemic episodes. This trial has also highlighted the need for careful selection of the insulin injection site to prevent excessively rapid transport to plasma.en
dc.identifier.citationThomas, F.L., Watson, A., Tomlinson, H., Borowczyk, H., Pretty, C.G., Fisk, L., Dickson, J.L., Chiew, Y.S., Shaw, G.M., Chase, J.G. (2014) mAGiC DRAGONS: A Protocol for Accurate Glycaemic Control in General Wards. Cape Town, South Africa: 19th World Congress of the International Federation of Automatic Control 2014 (IFAC), 24-29 Aug 2014.en
dc.identifier.urihttp://hdl.handle.net/10092/9627
dc.language.isoen
dc.publisherUniversity of Canterbury. Chemical and Process Engineeringen
dc.publisherUniversity of Canterbury. Mechanical Engineeringen
dc.rights.urihttps://hdl.handle.net/10092/17651en
dc.subject.anzsrcFields of Research::32 - Biomedical and clinical sciences::3202 - Clinical sciences::320208 - Endocrinologyen
dc.titlemAGiC DRAGONS: A Protocol for Accurate Glycaemic Control in General Wardsen
dc.typeConference Contributions - Published
Files
Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
12650144_Puff the mAGiC DRAGON_vSubmit_reviewed_finished.doc
Size:
1.86 MB
Format:
Microsoft Word
Download
Collections
Engineering: Conference Contributions