Elastomeric micropillar arrays for the study of protrusive forces in hyphal invasion

Type of content
Conference Contributions - Other
Publisher's DOI/URI
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Degree name
Publisher
University of Canterbury. Biological Sciences
University of Canterbury. Electrical and Computer Engineering
University of Canterbury. Biomolecular Interaction Centre
Journal Title
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Date
2015
Authors
Nock, V.
Tayagui, A.
Garrill, A.
Abstract

Fungi and Oomycetes are microorganisms that can be pathogenic and grow invasively causing significant economic losses and diseases1. • These organisms grow by extending the cell at the tip. This involves turgor pressure, cell wall yielding and a dynamic cytoskeleton, giving rise to a protrusive force2,3. •A Lab-on-a-Chip platform, with integrated force sensor based on elastomeric micro-pillars, is allowing us to study the molecular mechanisms which enable the generation of protrusive force at the tip of invasively-growing hyphae. •A maximum force of 16 μN was measured for the oomycete Achlya bisexualis cultured on the chip.

Description
Citation
Nock, V., Tayagui, A. and Garrill, A. (2015) Elastomeric micropillar arrays for the study of protrusive forces in hyphal invasion. Gyeongju, South Korea: 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2015), 25-29 Oct 2015.
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Ngā upoko tukutuku/Māori subject headings
ANZSRC fields of research
Field of Research::06 - Biological Sciences::0607 - Plant Biology::060702 - Plant Cell and Molecular Biology
Field of Research::09 - Engineering::0906 - Electrical and Electronic Engineering
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