Pilot Study to Confirm that Fat and Liver can be Distinguished by Spectroscopic Tissue Response on a Medipix-All-Resolution System-CT (MARS-CT)

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Conference Contributions - Published
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University of Canterbury. Physics and Astronomy
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Date
2009
Authors
Berg, K.B.
Carr, J.M.
Clark, M.J.
Cook, N.J.
Anderson, N.G.
Scott, N.J.
Butler, A.P.M.
Butler, P.H.
Butler, A.P.H.
MARS-CT Team
Abstract

NAFLD, liver component of the “metabolic” syndrome, has become the most common liver disease in western nations. Non-invasive imaging techniques exist, but have limitations, especially in detection and quantification of mild to moderate fatty liver. In this pilot study, we produced attenuation curves from biomedical-quality projection images of liver and fat using the MARS spectroscopic-CT scanner. Difficulties obtaining attenuation spectra after reconstruction demonstrated that standard reconstruction programs do not preserve spectral information.

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Citation
Berg, K.B., Carr, J.M., Clark, M.J., Cook, N.J., Anderson, N.G., Scott, N.J., Butler, A.P.M., Butler, P.H., Butler , A.P.H. (2009) Pilot Study to Confirm that Fat and Liver can be Distinguished by Spectroscopic Tissue Response on a Medipix-All-Resolution System-CT (MARS-CT). Dunedin, New Zealand: 4th International Conference on Advanced Materials and Nanotechnology (AMN-4), 8-12 Feb 2009.
Keywords
medipix, spectroscopic x-ray imaging, computed tomography, fatty liver, non-alcoholic fatty liver
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