Melzer, T.R.Myall, D.J.MacAskill, M.R.Pitcher, T.L.Livingston, L.Watts, R.Keenan, R.J.Dalrymple-Alford, J.C.Anderson, T.J.2016-06-242016-06-242015Melzer, T.R., Myall, D.J., MacAskill, M.R., Pitcher, T.L., Livingston, L., Watts, R., Keenan, R.J., Dalrymple-Alford, J.C., Anderson, T.J. (2015) Tracking Parkinson's Disease over One Year with Multimodal Magnetic Resonance Imaging in a Group of Older Patients with Moderate Disease. PloS one, 10(12), pp. e0143923, 14pp.http://hdl.handle.net/10092/12358Background & Objectives: Cross-sectional magnetic resonance imaging (MRI) suggests that Parkinson’s disease (PD) is associated with changes in cerebral tissue volume, diffusion tensor imaging metrics, and perfusion values. Here, we performed a longitudinal multimodal MRI study—including structural, diffusion tensor imaging (DTI), and perfusion MRI—to investigate progressive brain changes over one year in a group of older PD patients at a moderate stage of disease.enJournal ArticleField of Research::11 - Medical and Health Sciences::1109 - NeurosciencesField of Research::17 - Psychology and Cognitive Sciences::1701 - Psychology::170101 - Biological Psychology (Neuropsychology, Psychopharmacology, Physiological Psychology)Field of Research::11 - Medical and Health Sciences::1103 - Clinical Sciences::110320 - Radiology and Organ Imaginghttps://doi.org/10.1371/journal.pone.0143923