Virtual Patients for Managing Mechanical Ventilation in the ICU

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Conference Contributions - Other
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Chase, Geoff
Morton, Sophie Elizabeth
Knopp, Jennifer L.

— Mechanical ventilation (MV) is a primary therapy in the intensive care unit (ICU). Sub-optimal ventilator settings can cause lung damage, but optimal selection is confounded by significant inter- and intra- patient variability in response to MV. Titrating PEEP (positive end expiratory pressure) to minimum elastance is a proven approach. However, in clinical practice finding this value is difficult. A predictive elastance model, or virtual patient, would directly assess a current PEEP level should be changed based on whether a nearby PEEP had lower elastance, as well as enable safe PEEP titration. A predictive, virtual patient model for MV in the ICU is presented.

Chase G, Morton SE, Knopp JL (2019). Virtual Patients for Managing Mechanical Ventilation in the ICU. Berlin, Germany: 41st IEEE Engineering in Medicine and Biology Conference (IEEE EMBC). 23/07/2019-27/07/2019.
Ngā upoko tukutuku/Māori subject headings
ANZSRC fields of research
Fields of Research::40 - Engineering::4003 - Biomedical engineering::400308 - Medical devices
Fields of Research::40 - Engineering::4003 - Biomedical engineering::400305 - Biomedical instrumentation
Fields of Research::32 - Biomedical and clinical sciences::3202 - Clinical sciences::320212 - Intensive care