Natural disasters and other crises present methodological challenges to organizational researchers. While these challenges are well canvassed in the literature, less attention has been paid to understanding how distinct crisis events may present, not only unique challenges, but also important opportunities for research. In this chapter, we draw on our collective experience of conducting post-earthquake research and compare this with the COVID-19 pandemic context in order to identify and discuss the inherent vulnerabilities associated with disaster studies and the subsequent methodological challenges and opportunities that researchers might encounter. Adopting a critical perspective, the chapter grapples with some of the more contentious issues associated with research in a disaster and crisis context including aspects of stakeholder engagement, ethics, reciprocity, inequality and vulnerability.