Medipix-based Spectral Micro-CT? (2012)
Type of ContentJournal Article
PublisherUniversity of Canterbury. Physics and Astronomy
AuthorsYu, H., Xu, Q., He, P., Bennett, J., Amir, R., Dobbs, B., Mou, X., Wei, B., Butler, A., Butler, P., Wang, G.show all
Since Hounsfield’s Nobel Prize winning breakthrough decades ago, x-ray CT has been widely applied in the clinical and preclinical applications - producing a huge number of tomographic gray-scale images. However, these images are often insufficient to distinguish crucial differences needed for diagnosis. They have poor soft tissue contrast due to inherent photon-count issues, involving high radiation dose. By physics, the x-ray spectrum is polychromatic, and it is now feasible to obtain multi-energy, spectral, or true-color, CT images. Such spectral images promise powerful new diagnostic information. The emerging Medipix technology promises energy-sensitive, high-resolution, accurate and rapid x-ray detection. In this paper, we will review the recent progress of Medipix-based spectral micro-CT with the emphasis on the results obtained by our team. It includes the state-of-the-art Medipix detector, the system and method of a commercial MARS (Medipix All Resolution System) spectral micro-CT, and the design and color diffusion of a hybrid spectral micro-CT.
CitationHengyong Yu, Qiong Xu, Peng He, James Bennett, Raja Amir, Bruce Dobbs, Xuanqin Mou, Biao Wei, Anthony Butler, Phillip Butler, Ge Wang (2012) Medipix-based Spectral Micro-CT?. CT Theory and Applications, 21(4), pp. 583-596.
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Keywordsmulti-energy; spectral imaging; Medipix detector; Medipix all resolution system (MARS); hybrid spectral micro-CT; statistical iteration reconstruction; principle component analysis.
ANZSRC Fields of Research11 - Medical and Health Sciences::1103 - Clinical Sciences::110320 - Radiology and Organ Imaging
09 - Engineering::0903 - Biomedical Engineering::090303 - Biomedical Instrumentation