Continuous glucose monitoring in newborn infants: How do errors in calibration measurements affect detected hypoglycemia?
Neonatal hypoglycemia is common and can cause serious brain injury. Continuous glucose monitoring (CGM) could improve hypoglycemia detection, while reducing the number of blood glucose (BG) measurements. Calibration algorithms use BG measurements to convert sensor signals into CGM data. Thus, inaccuracies in calibration BG measurements directly affect CGM values and any metrics calculated from them. This research aimed to quantify the effect of timing delays and calibration BG measurement errors on hypoglycemia metrics in newborn infants.