Estimating Relative Change in Ventricular Stroke Work from Aortic Pressure Alone: Proof of Concept Study
Continuous Ventricular Stroke Work (VSW) estimation requires accurate estimate of both stroke volume and aortic pressure. However, accurate beat-to-beat stroke volume measurement is highly invasive and thus typically unavailable in clinical practice. This study analyses the accuracy of a model-based method estimating relative change in VSW using only aortic pressure measurements. Using data from porcine experiment, the correlation coefficient was determined between the relative change of VSW from directly measured data and the model-based estimate of VSW. The result showed good agreement with, R=0.71. The model accurately captured the trend of VSW using only aortic pressure measurements and thus offers significant clinical value in early diagnosis and improving care for cardiovascular dysfunction.