Rfam 11.0: 10 years of RNA families
Author
Burge, S.W.
Daub, J.
Eberhardt, R.
Tate, J.
Barquist, L.
Nawrocki, E.P.
Eddy, S.R.
Gardner, P.P.
Bateman, A.
Date
2013Permanent Link
http://hdl.handle.net/10092/9537The Rfam database (available via the website at http://rfam.sanger.ac.uk and through our mirror at http://rfam.janelia.org) is a collection of non-coding RNA families, primarily RNAs with a conserved RNA secondary structure, including both RNA genes and mRNA cis-regulatory elements. Each family is represented by a multiple sequence alignment, predicted secondary structure and covariance model. Here we discuss updates to the database in the latest release, Rfam 11.0, including the introduction of genome-based alignments for large families, the introduction of the Rfam Biomart as well as other user interface improvements. Rfam is available under the Creative Commons Zero license.