The effect of physical activity on serum lipids, lipoprotein, and apolipoproteins

Type of content
Journal Article
Publisher's DOI/URI
Thesis discipline
Degree name
Publisher
University of Canterbury. School of Sport & Physical Education
Journal Title
Journal ISSN
Volume Title
Language
Date
2010
Authors
Shearman, J.
Micklewright, D.
Hardcastle, J.
Hamlin, M.
Draper, N.
Abstract

Objective: The aim of this study was to measure apolipoprotein-A1 and apolipoprotein-B serum concentrations during a physical activity program. Serum apolipoprotein concentrations may be a more sensitive indicator of coronary heart disease (CHD) risk than total cholesterol, triglycerides, low density lipoproteins and high density lipoproteins. Design: Thirty-seven sedentary, healthy adult males were randomly allocated to an exercise group (n=20) who underwent 12 weeks of aerobic physical activity or a sedentary group (n=17) who acted as nonexercising controls. Results: The exercise group increased their aerobic capacity (from 33±4 mL•kg-1•min-1 to 40±4 mL•kg-1•min-1) but the sedentary group did not. The percentage of body fat decreased in the exercise group (from 21.8% to 19.5%) but remained unchanged in the sedentary group. Serum cholesterol, lipoprotein and apolipoprotein concentrations did not change but serum triglyceride concentrations were reduced in the exercise group (from 1.8±1.3 mmol•L-1 to 1.2±0.4 mmol•L-1, p<0.05). The Apo-A1:Apo-B ratio increased in the exercise group (from 1.17±0.22 to 1.±0.27, p<0.05) but not in the sedentary group. Conclusion: Apolipoprotein concentrations in sedentary males are no more sensitive than other serum lipid concentrations but are appropriate for monitoring CHD risk-factor change during short-term light exercise interventions.

Description
Citation
Shearman, J., Micklewright, D., Hardcastle, J., Hamlin, M., Draper, N. (2010) The effect of physical activity on serum lipids, lipoprotein, and apolipoproteins. Archives of Exercise in Health and Disease, 1(2), pp. 43-49.
Keywords
physical activity, serum lipids, apolipoproteins
Ngā upoko tukutuku/Māori subject headings
ANZSRC fields of research
Fields of Research::32 - Biomedical and clinical sciences::3205 - Medical biochemistry and metabolomics::320504 - Medical biochemistry - lipids
Fields of Research::42 - Health sciences::4207 - Sports science and exercise::420702 - Exercise physiology
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