Pancreatic Insulin Secretion in Critically Ill Patients
Glucose-insulin pharmacokinetic-pharmacodynamic (PK-PD) models can be used for improved glycemic control of critically ill patients. A key component of glucose-insulin PK-PD models is pancreatic insulin secretion. There is limited data in the literature quantifying insulin secretion in critically ill patients at physiologic levels. This study creates a model pancreatic insulin secretion in critically ill patients to improve glucose-insulin system modeling.