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    Cardiovascular system modelling of heart-lung interaction during mechanical ventilation

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    Author
    Smith, B.W.
    Andreassen, S.
    Shaw, G.M.
    Rees, S.E.
    Chase, J.G.
    Date
    2006
    Permanent Link
    http://hdl.handle.net/10092/57

    Choosing suitable ventilation strategies for critically ill patients with lung disorders involves considering the difficult and poorly understood trade-off between achieving adequate ventilation, while maintaining suitable perfusion. This study presents a minimal cardiovascular system model that includes variations in pulmonary vascular resistance during mechanical ventilation. The model is shown to capture transient haemodynamics from experimentally measured data. It also enables investigation into the effects of time varying resistance on pulmonary haemodynamics. The study shows the potential usefulness of this model in a tool to assist clinical staff in optimising ventilation pressures while maintaining adequate pulmonary perfusion

    Subjects
    Biomedical systems
     
    Physiological models
     
    Dynamic modelling
     
    Dynamic models
     
    Lumped constant models
     
    Fields of Research::290000 Engineering and Technology::291500 Biomedical Engineering::291504 Biomechanical engineering
     
    Fields of Research::320000 Medical and Health Sciences::320600 Medical Physiology::320603 Systems physiology
    Collections
    • Engineering: Conference Contributions [1920]
    Rights
    https://canterbury.libguides.com/rights/ir

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