Control and measurement of hypoxia in microfluidic cancer assays (2011)
AuthorsNock, V., Murray, L., Alkaisi, M.M., Evans, J.J.show all
In this paper we will demonstrate spatially-resolved visualization of oxygen dissolved in a liquid medium and introduce two microfluidic devices for cell-culture experiments with integrated oxygen control. We will further show how these devices can be used to retain clusters or even individual cells within larger populations under hypoxic conditions, a capability which will allow the evaluation of cancer drugs on a cell-to-cell basis. In general, the combination of the oxygen sensor system with microfluidic culture devices has the potential to significantly improve the relevance of current cancer drug assays.
CitationNock, V., Murray, L., Alkaisi, M.M., Evans, J.J. (2011) Control and measurement of hypoxia in microfluidic cancer assays. Auckland, New Zealand: Benchtop to Bedside - The New Zealand Society of Oncology Conference (NZSO 2011), 12-13 May 2011.
This citation is automatically generated and may be unreliable. Use as a guide only.