University of Canterbury Home
    • Admin
    UC Research Repository
    UC Library
    JavaScript is disabled for your browser. Some features of this site may not work without it.
    View Item 
    1. UC Home
    2. Library
    3. UC Research Repository
    4. Faculty of Health
    5. Health: Theses and Dissertations
    6. View Item
    1. UC Home
    2.  > 
    3. Library
    4.  > 
    5. UC Research Repository
    6.  > 
    7. Faculty of Health
    8.  > 
    9. Health: Theses and Dissertations
    10.  > 
    11. View Item

    The influence of inhaled corticosteroids on normal voice production in adults : an acoustic study (2010)

    Thumbnail
    View/Open
    thesis_fulltext.pdf (797.2Kb)
    Type of Content
    Theses / Dissertations
    UC Permalink
    http://hdl.handle.net/10092/4964
    http://dx.doi.org/10.26021/9555
    
    Thesis Discipline
    Health Sciences
    Degree Name
    Master of Health Sciences
    Publisher
    University of Canterbury. Health Sciences Centre
    Collections
    • Health: Theses and Dissertations [292]
    Authors
    Sahrawat, Ramesh
    show all
    Abstract

    Corticosteroids are the most potent and reliable of the available agents among the anti-inflammatory drugs, and have assumed a major role in the management of asthma. This has subsequently resulted in the global widespread use of inhaled corticosteroids (ICS). A variety of studies have been undertaken to examine the effects of ICS on voice production among people with asthma. Most research suggests that the long-term use of ICS has a negative effect on voice production. However, the results of these studies are limited because of the reliance upon examining an asthmatic population and not consistently recording the dose prescribed. As a result, one cannot exclude that some of the voice problems may have been previously caused by asthma and thus, the contributing effects of ICS are obscured. Therefore, an ideal approach to examine the influence of ICS on voice is to test its short-term effects on healthy individuals, using a specific ICS (Fluticasone Propionate) at a fixed dose (1000 µg/Day). Thirty healthy adults (15 females & 15 males) aged between 18 to 30 years participated in this study. All participants were non-smokers with no history of speech, language or voice disorder. No participants had a history of asthma, respiratory illness hospital admission or inhaler use within the past 3 months. All participants followed the treatment regime often prescribed by physicians (in Canterbury region) for treating asthma (500 µg in morning & 500 µg in evening). Each participant self administered (inhaled) two puffs of ICS in the morning and again in the evening over a six day period. Voice samples were audio-recorded prior to undergoing the ICS regime, at various points during the ICS regime, and at the conclusion of ICS regime. Each participant’s audio-recorded samples were submitted for acoustic analysis using a commercially available speech analysis system (CSL 4300B, Kay Elemetrics, 1994). Three measures were performed, (1) vocal fundamental frequency (F0), (2) long-time spectral analysis (LTAS) and (3) formant frequency and formant frequency bandwidth. The results of this study indicate that ICS does have an effect on acoustic properties of voice. These effects were more evident in connected speech compared to isolated vowel productions. In particular, the spectral tilt and first spectral peak of continuous speech samples were found to change from baseline. The current results are discussed in regard to the phonatory deterioration associated with ICS use. The present study provides a framework for developing ICS treatment for respiratory disease in the phase of minimizing adverse effects on voice.

    Keywords
    asthma; inhaled corticosteroids; voice; acoustic analysis
    Rights
    Copyright Ramesh Sahrawat
    https://canterbury.libguides.com/rights/theses

    Related items

    Showing items related by title, author, creator and subject.

    • Modelling the influence of radiata pine log variables on structural lumber production 

      Gavilán E; Alzamora RM; Sáez K; Elissetche JP; Pinto A; Apiolaza, Luis (2023)
      We run logit models to explain the variability of Pinus radiata structural lumber in 71 second and third unpruned logs. The response variable was the proportion of lumber with a static modulus of elasticity greater or ...
    • Neurophysiological evidence for the influence of phonological and semantic neighbourhood densities on word production in children and adults. 

      Hansmann, Doreen (University of Canterbury, 2016)
      This thesis aimed to explore the effects of phonological and semantic neighbourhood densities during word production in children. Neighbourhood density refers to the number of words that are related to each other, and ...
    • Native language influence on brass instrument performance: An application of generalized additive mixed models (GAMMs) to midsagittal ultrasound images of the tongue 

      Derrick, Donald; Heyne M; Al-Tamimi J (2019)
      This paper presents the findings of an ultrasound study of 10 New Zealand English and 10 Tongan-speaking trombone players, to determine whether there is an influence of native language speech production on trombone ...
    Advanced Search

    Browse

    All of the RepositoryCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThesis DisciplineThis CollectionBy Issue DateAuthorsTitlesSubjectsThesis Discipline

    Statistics

    View Usage Statistics
    • SUBMISSIONS
    • Research Outputs
    • UC Theses
    • CONTACTS
    • Send Feedback
    • +64 3 369 3853
    • ucresearchrepository@canterbury.ac.nz
    • ABOUT
    • UC Research Repository Guide
    • Copyright and Disclaimer
    • SUBMISSIONS
    • Research Outputs
    • UC Theses
    • CONTACTS
    • Send Feedback
    • +64 3 369 3853
    • ucresearchrepository@canterbury.ac.nz
    • ABOUT
    • UC Research Repository Guide
    • Copyright and Disclaimer