The Spread of Tomato Yellow Leaf Curl Virus from the Middle East to the World (2010)

View/ Open
Type of Content
Journal ArticlePublisher
University of Canterbury. Biological SciencesCollections
- Science: Journal Articles [1139]
Authors
Abstract
The ongoing global spread of Tomato yellow leaf curl virus (TYLCV; Genus Begomovirus, Family Geminiviridae) represents a serious looming threat to tomato production in all temperate parts of the world. Whereas determining where and when TYLCV movements have occurred could help curtail its spread and prevent future movements of related viruses, determining the consequences of past TYLCV movements could reveal the ecological and economic risks associated with similar viral invasions. Towards this end we applied Bayesian phylogeographic inference and recombination analyses to available TYLCV sequences (including those of 15 new Iranian full TYLCV genomes) and reconstructed a plausible history of TYLCV’s diversification and movements throughout the world. In agreement with historical accounts, our results suggest that the first TYLCVs most probably arose somewhere in the Middle East between the 1930s and 1950s (with 95% highest probability density intervals 1905–1972) and that the global spread of TYLCV only began in the 1980s after the evolution of the TYLCV-Mld and -IL strains. Despite the global distribution of TYLCV we found no convincing evidence anywhere other than the Middle East and the Western Mediterranean of epidemiologically relevant TYLCV variants arising through recombination. Although the region around Iran is both the center of present day TYLCV diversity and the site of the most intensive ongoing TYLCV evolution, the evidence indicates that the region is epidemiologically isolated, which suggests that novel TYLCV variants found there are probably not direct global threats. We instead identify the Mediterranean basin as the main launch-pad of global TYLCV movements.
Citation
Lefeuvre, P., Martin, D.P., Harkins, G., Lemey, P., Gray, A.J.A., Meredith, S., Lakay, F., Monjane, A., Lett, J.M., Varsani, A., Heydarnejad, J. (2010) The Spread of Tomato Yellow Leaf Curl Virus from the Middle East to the World. PLoS Pathogens, 6(10), pp. e1001164.This citation is automatically generated and may be unreliable. Use as a guide only.
ANZSRC Fields of Research
06 - Biological Sciences::0607 - Plant Biology::060704 - Plant PathologyRelated items
Showing items related by title, author, creator and subject.
-
East African cassava mosaic-like viruses from Africa to Indian ocean islands: Molecular diversity, evolutionary history and geographical dissemination of a bipartite begomovirus
De Bruyn, A.; Villemot, J.; Lefeuvre, P.; Villar, E.; Hoareau, M.; Harimalala, M.; Abdoul-Karime, A.L.; Abdou-Chakour, C.; Reynaud, B.; Harkins, G.W.; Varsani, A.; Martin, D.P.; Lett, J-M. (University of Canterbury. Biological SciencesUniversity of Canterbury. Biomolecular Interaction Centre, 2012)Cassava (Manihot esculenta) is a major food source for over 200 million sub-Saharan Africans. Unfortunately, its cultivation is severely hampered by cassava mosaic disease (CMD). Caused by a complex of bipartite cassava ... -
Evidence of pervasive biologically functional secondary-structures within the genomes of eukaryotic single-stranded DNA viruses
Muhire, B.M.; Golden, M.; Murrell, B.; Lefeuvre, P.; Lett, J-M.; Gray, A.; Poon, A.Y.F.; Ngandu, N.K.; Semegni, Y.; Tanov, E.P.; Monjane, A.L.; Harkins, G.W.; Varsani, A.; Shepherd, D.N.; Martin, D.P. (University of Canterbury. Biological SciencesUniversity of Canterbury. Biomolecular Interaction Centre, 2014)Single-stranded DNA (ssDNA) viruses have genomes that are potentially capable of forming complex secondary structures through Watson-Crick base pairing between their constituent nucleotides. A few of the structural elements ... -
Geometagenomics illuminates the impact of agriculture on the distribution and prevalence of plant viruses at the ecosystem scale
Bernardo P; Charles-Dominique T; Barakat M; Ortet P; Fernandez E; Filloux D; Hartnady P; Rebelo TA; Cousins SR; Mesleard F; Cohez D; Yavercovski N; Varsani A; Harkins GW; Peterschmitt M; Malmstrom CM; Martin DP; Roumagnac P (2018)© 2018 International Society for Microbial Ecology All rights reserved. Disease emergence events regularly result from human activities such as agriculture, which frequently brings large populations of genetically uniform ...