Patient specific model of the cardiovascular system during septic shock
Sepsis is a most complex and serious systemic response to infection and is one of the leading causes for morbidity and mortality in the critical care setting. In this research, a porcine model of induced endotoxic shock without hemofiltration is analyzed and the parameters of a previously validated cardiovascular system (CVS) model are identified. For the first time the identification process is applied to strictly right ventricle signals and no left ventricle signals were measured. This significantly reduced data set is of particular clinical importance, as often only limited data, such as data from only one of the ventricles, is available in Intensive Care Units (ICU).