Blood glucose modelling and control for pre-term infants

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Conference Contributions - Other
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University of Canterbury. Mechanical Engineering
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Date
2008
Authors
LeCompte, A.J.
Chase, Geoff
Shaw, Geoff
Lynn, A.
Russell, G.
Abstract

Hyperglycemia (high blood sugar levels) occurs in 40-80% of very low birth weight infants in the neonatal intensive care unit (NICU). This condition has been linked to mortality and morbidities including retinopathy of prematurity, osmotic diuresis, reduced immune system performance and sepsis. Insulin therapy can control hyperglycaemia and promote growth, but increases the risk of dangerous low levels of blood glucose. The goal of this model is to provide dosing recommendations for attending clinicians. The model is used for two tasks: predict future blood glucose concentration for real-time control, and perform simulated trials to optimise control strategies.

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Citation
LeCompte, A.J., Chase, J.G., Shaw, G.M., Lynn, A., Russell, G. (2008) Blood glucose modelling and control for pre-term infants. Christchurch, New Zealand: 2008 Engineering & Physical Sciences in Medicine and Australian Biomedical Engineering Conference, 16-20 Nov 2008.
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