Now showing items 1-10 of 175
Watershed Urbanization Linked to Differences in Stream Bacterial Community Composition
Urbanization strongly influences headwater stream chemistry and hydrology, but little is known about how these conditions impact bacterial community composition. We predicted that urbanization would impact bacterial ...
Quaternary structure is an essential component that contributes to the sophisticated allosteric regulation mechanism in a key enzyme from Mycobacterium tuberculosis
The first enzyme of the shikimate pathway, 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (DAH7PS), adopts a range of distinct allosteric regulation mechanisms in different organisms, related to different quaternary ...
Conservation genetics of two threatened frogs from the Mambilla highlands, Nigeria
Amphibians are the vertebrate group with the highest number of species threatened with extinction, and habitat loss and fragmentation are considered to be among the leading causes of their declines and extinctions. Little ...
Interactive effects of land use, temperature, and predators determine native and invasive mosquito distributions
1. Land-use and climate change could alter the distribution of both native and exotic mosquitoes by changing abiotic and biotic characteristics of freshwater habitats. We initially studied the influence of land use on ...
Does a species' extinction-proneness predict its contribution to nestedness? A test using a sunbird-tree visitation network
Animal pollinators and the plants they pollinate depend on networks of mutualistic partnerships and more broadly on the stability of such networks. Based mainly on insect-plant visitation networks, theory predicts that ...
Cofactor Tail Length Modulates Catalysis of Bacterial F420-Dependent Oxidoreductases
F420 is a microbial cofactor that mediates a wide range of physiologically important and industrially relevant redox reactions, including in methanogenesis and tetracycline biosynthesis. This deazaflavin comprises a ...
P-TEFb: finding its ways to release promoter-proximally paused RNA Polymerase II
The release of a paused Pol II depends on the recruitment of P-TEFb. Recent studies showed that both active P-TEFb and inactive P-TEFb (7SK snRNP) can be recruited to the promoter regions of global genes by different ...
The scaling of population persistence with carrying capacity does not asymptote in populations of a fish experiencing extreme climate variability.
Despite growing concerns regarding increasing frequency of extreme climate events and declining population sizes, the influence of environmental stochasticity on the relationship between population carrying capacity and ...
Multiple P-TEFbs cooperatively regulate the release of promoter-proximally paused RNA polymerase II
The association of DSIF and NELF with initiated RNA Polymerase II (Pol II) is the general mechanism for inducing promoter-proximal pausing of Pol II. However, it remains largely unclear how the paused Pol II is released ...