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7,8-Dihydroneopterin and its effect on the formation of foam cells.
(University of Canterbury. School of Biological Sciences, 2015)
Atherosclerosis (Heart Disease) is an inflammatory disease caused by the formation of plaque within the arterial wall. In response to inflammation, monocytes enter the artery wall, differentiate into macrophages and take ...
Mechanisms of 7,8-dihydroneopterin protection of macrophages from cytotoxicity
(University of Canterbury. Biological Sciences, 2013)
Gamma-interferon stimulates human macrophages to produce of 7,8-dihydroneopterin (7,8-NP). 7,8-NP and its oxidation product neopterin are excellent inflammatory markers for a variety of chronic conditions, including ...