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7,8-Dihydroneopterin and its effect on the formation of foam cells.
(University of Canterbury. School of Biological Sciences, 2015)
Atherosclerosis (Heart Disease) is an inflammatory disease caused by the formation of plaque within the arterial wall. In response to inflammation, monocytes enter the artery wall, differentiate into macrophages and take ...
Macrophage Activation and Differentiation with Cholesterol Crystals
(University of Canterbury. Biological Sciences, 2012)
Cholesterol crystals have been linked to activation of the NLRP3 inflammasome and the formation of foreign body giant cells (FBGCs). It has been hypothesized that FBGCs have a role in advanced atherosclerotic plaque ...