Now showing items 1-2 of 2
Mechanisms of 7,8-dihydroneopterin protection of macrophages from cytotoxicity
(University of Canterbury. Biological Sciences, 2013)
Gamma-interferon stimulates human macrophages to produce of 7,8-dihydroneopterin (7,8-NP). 7,8-NP and its oxidation product neopterin are excellent inflammatory markers for a variety of chronic conditions, including ...
7,8-Dihydroneopterin-mediated protection of low density lipoprotein, but not human macrophages, from oxidative stress
(University of Canterbury. Biological Sciences, 2006)
Any lipoproteins and cells present in the inflammatory environment of atherosclerotic plaques are likely to be exposed to high levels of oxidative stress. As 7,8-dihydroneopterin (7,8-NP) is synthesized by interferon-Î³ ...