Prediction of Sphingosine protein-coding regions with a self adaptive spectral rotation method (2019)
Type of ContentJournal Article
PublisherPublic Library of Science (PLoS)
AuthorsLi Z, Guan Y, Yuan X, Zheng P, Zhu Hshow all
© 2019 Li et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Identifying protein coding regions in DNA sequences by computational methods is an active research topic. Welan gum produced by Sphingomonas sp. WG has great application potential in oil recovery and concrete construction industry. Predicting the coding regions in the Sphingomonas sp. WG genome and addressing the mechanism underlying the explanation for the synthesis of Welan gum metabolism is an important issue at present. In this study, we apply a self adaptive spectral rotation (SASR, for short) method, which is based on the investigation of the Triplet Periodicity property, to predict the coding regions of the whole-genome data of Sphingomonas sp. WG without any previous training process, and 1115 suspected gene fragments are obtained. Suspected gene fragments are subjected to a similarity search against the non-redundant protein sequences (nr) database of NCBI with blastx, and 762 suspected gene fragments have been labeled as genes in the nr database.
CitationLi Z, Guan Y, Yuan X, Zheng P, Zhu H (2019). Prediction of Sphingosine protein-coding regions with a self adaptive spectral rotation method. PLoS ONE. 14(4). e0214442-.
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ANZSRC Fields of Research01 - Mathematical Sciences::0102 - Applied Mathematics::010202 - Biological Mathematics
06 - Biological Sciences::0601 - Biochemistry and Cell Biology::060102 - Bioinformatics