Tracking Parkinson's Disease over One Year with Multimodal Magnetic Resonance Imaging in a Group of Older Patients with Moderate Disease
Author
Melzer, T.R.
Myall, D.J.
MacAskill, M.R.
Pitcher, T.L.
Livingston, L.
Watts, R.
Keenan, R.J.
Dalrymple-Alford, J.C.
Anderson, T.J.
Date
2015Permanent Link
http://hdl.handle.net/10092/12358Background & Objectives: Cross-sectional magnetic resonance imaging (MRI) suggests that Parkinson’s disease (PD) is associated with changes in cerebral tissue volume, diffusion tensor imaging metrics, and perfusion values. Here, we performed a longitudinal multimodal MRI study—including structural, diffusion tensor imaging (DTI), and perfusion MRI—to investigate progressive brain changes over one year in a group of older PD patients at a moderate stage of disease.