A Deviation in BG dynamics during liver transplantation comparing ICU patients: a model-based approach

Abstract

A proper glycemic control would beneficial affect on the outcomes of the liver-transplantation. Model based validated tight glycemic control protocol, STAR exists for ICU treatments. The validated metabolic model ICING for STAR differ in the blood glucose dynamics. By localizing the places of the extraordinary LT patients dynamics we can specify modifications on the ICU patient model. Based on the analyzes of ICING model, these dynamics mainly occurs in the 1) pre-anhepatic phase at the beginning of the surgery, 2) at the portal vein reperfusion and 3) in the post-anhepatic phase before 500 minutes from the reperfusion.