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    Preschool Language Development of Children Born to Women with an Opioid Use Disorder. (2021)

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    Published version (853.5Kb)
    Type of Content
    Journal Article
    UC Permalink
    https://hdl.handle.net/10092/102032
    
    Publisher's DOI/URI
    http://doi.org/10.3390/children8040268
    
    Publisher
    MDPI AG
    ISSN
    2227-9067
    Language
    eng
    Collections
    • Health: Journal Articles [151]
    Authors
    Bone RM
    Lee SJ
    Gillon G
    Kim, Hyun Min cc
    McNeill, Brigid cc
    Woodward, Lianne cc
    show all
    Abstract

    Increasing evidence suggests that prenatal exposure to opioids may affect brain development, but limited data exist on the effects of opioid-exposure on preschool language development. Our study aimed to characterize the nature and prevalence of language problems in children prenatally exposed to opioids, and the factors that support or hinder language acquisition. A sample of 100 children born to pregnant women in methadone maintenance treatment and 110 randomly identified non-exposed children were studied from birth to age 4.5 years. At 4.5 years, 89 opioid-exposed and 103 non-exposed children completed the preschool version of the Clinical Evaluation of Language Fundamentals (CELF-P) as part of a comprehensive neurodevelopmental assessment. Children prenatally exposed to opioids had poorer receptive and expressive language outcomes at age 4.5 years compared to non-opioid exposed children. After adjustment for child sex, maternal education, other pregnancy substance use, maternal pregnancy nutrition and prenatal depression, opioid exposure remained a significant independent predictor of children's total CELF-P language score. Examination of a range of potential intervening factors showed that a composite measure of the quality of parenting and home environment at age 18 months and early childhood education participation at 4.5 years were important positive mediators.

    Citation
    Kim HM, Bone RM, McNeill B, Lee SJ, Gillon G, Woodward LJ (2021). Preschool Language Development of Children Born to Women with an Opioid Use Disorder.. Children (Basel, Switzerland). 8(4). 268-268.
    This citation is automatically generated and may be unreliable. Use as a guide only.
    Keywords
    CELF-P; child; language; methadone; neonatal abstinence syndrome; opioid; outcome
    ANZSRC Fields of Research
    39 - Education::3903 - Education systems::390302 - Early childhood education
    47 - Language, communication and culture::4704 - Linguistics::470402 - Child language acquisition
    Rights
    All rights reserved unless otherwise stated
    http://hdl.handle.net/10092/17651

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