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Evolution of insulin sensitivity and its variability in out of hospital cardiac arrest (OHCA) patients treated with hypothermia (2014)

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Journal Article
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http://hdl.handle.net/10092/10140

Publisher's DOI/URI
https://doi.org/10.1186/s13054-014-0586-x

Publisher
University of Canterbury. Mechanical Engineering
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Authors
Sah Pri, A.
Chase, Geoff cc
Pretty, C.G.
Shaw, Geoff cc
Preiser, J-C.
Vincent, J-L.
Oddo, M.
Taccone, F.
Penning, S.
Desaive, T.
Abstract

Therapeutic hypothermia (TH) is often used to treat out-of-hospital cardiac arrest (OHCA) patients who also often simultaneously receive insulin for stress-induced hyperglycaemia. However, the impact of TH on systemic metabolism and insulin resistance in critical illness is unknown. This study analyses the impact of TH on metabolism, including the evolution of insulin sensitivity (SI) and its variability, in patients with coma after OHCA.

Citation
Sah Pri, A., Chase, J.G., Pretty, C.G., Shaw, G.M., Preiser, J-C., Vincent, J-L., Oddo, M., Taccone, F., Penning, S., Desaive, T. (2014) Evolution of insulin sensitivity and its variability in out of hospital cardiac arrest (OHCA) patients treated with hypothermia. Critical Care, 18, pp. 586.
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ANZSRC Fields of Research
32 - Biomedical and clinical sciences::3201 - Cardiovascular medicine and haematology::320101 - Cardiology (incl. cardiovascular diseases)
32 - Biomedical and clinical sciences::3201 - Cardiovascular medicine and haematology::320102 - Haematology
40 - Engineering::4003 - Biomedical engineering::400303 - Biomechanical engineering
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