Parallel screening of single zoospore germination and germ tube protrusive forces (2020)
AuthorsSun Y, Tayagui A, Garrill A, Nock Vshow all
This paper reports the parallel screening of zoospore germination and protrusive forces of germ tubes on a labon-a-chip platform, integrating valve-based single zoospore compartmentalization with micropillar force sensing. Individually-controllable, normally-closed microvalves were optimized to facilitate zoospore compartmentalization in measurement channels containing traps and sensing pillars. Performance was evaluated using microspheres and zoospores of the oomycete Achlya bisexualis. By parallelizing the screening, the platform will support fundamental studies and aid in the discovery of new compounds to control fungal and oomycete pathogens.
CitationSun Y, Tayagui A, Garrill A, Nock V (2020). Parallel screening of single zoospore germination and germ tube protrusive forces. Virtual: 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences. 04/10/2020-08/10/2020. 909-910.
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