Continuous glucose monitoring in newborn infants: Effect of calibration measurements and detected hypoglycaemia

Abstract

Neonatal glycaemia is highly variable and can cause serious brain injury if uncontrolled [1]. However, monitoring infants’ blood glucose (BG) levels via frequent BG measurements is not achievable due to a lack of blood and the distressed caused to both mother and child. Hence, the risk of neonatal hypoglycaemia is yet to be negated. Continuous glucose monitoring (CGM) could improve hypoglycaemia detection, while reducing the number of BG measurements [2]. CGM and BG are not necessarily well correlated, and this research aims to quantify the effect of timing delays and calibration errors on the risk of hypoglycaemia in newborn infants.